Les anomalies du cortex cérébral chez des enfants et adolescents avec de troubles de déficit d'attention et hyperactivité (TDAH)

 

Petit résumé :Des anomalies morphologiques ont été constatées dans le cortex cérébral des enfants atteints de TDAH notamment au niveau du cortex préfrontal, ainsi que le cortex temporal antérieur, cortex temporal postérieur, et pariétal inférieur.

We used high-resolution MRI and surface-based, computational image analytic techniques to map regional brain size and grey-matter abnormalities at the cortical surface in a group of 27 children and adolescents with attention-deficit hyperactivity disorder and 46 controls, who were group-matched by age and sex.
Abnormal morphology was noted in the frontal cortices of patients with attention-deficit hyperactivity disorder, with reduced regional brain size localised mainly to inferior portions of dorsal prefrontal cortices bilaterally. Brain size was also reduced in anterior temporal cortices bilaterally. Prominent increases in grey matter were recorded in large portions of the posterior temporal and inferior parietal cortices bilaterally.
The frontal, temporal, and parietal regions are heteromodal association cortices that constitute a distributed neural system, which subserves attention and behavioural inhibition. We have identified region-specific anatomical abnormalities in cortical components of attentional systems, which may help better account for the symptoms of attention-deficit hyperactivity disorder.

Sowell, E. R. et al. Cortical abnormalities in children and adolescents with attention deficit hyperactivity disorder. Lancet 362, 1699-1707

 

Programme CerebroStim :

Le programme cerebrostim est destiné aux enfants et adultes souffrant d'un spectre large de troubles y compris les troubles envahissants de développement, troubles de déficit d'attention, hyperactivité, dyslexie, troubles de comportements, etc. L'objectif est d'analyser les déficits de fonctionnement des parties du cerveau et planifier un programme de rééducation pour stimuler et renforcer les endroits ou hémisphères faibles.

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